stem cells, basal cells, esophagus, esophagitis, Barrett's esophagus, esophageal cancer, lung development & regeneration.

We investigate the mechanisms of epithelial morphogenesis and maintenance. We are also interested in how stem cell abnormalities lead to diseases of the esophagus and lung. We have successfully built mouse models of EA/TEF, eosinophilic esophagitis, esophageal squamous cell carcinoma, bronchiopulmonary dysplasia (BPD) and lung fibrosis. Additionally, we use human embryonic stem cells to model some of these diseases, meanwhile searching for novel drugs to treat them.


​BB 810, 650 West, 168th Street,

Columbia University Medical Center

New York, NY 10032

Telephone: 212-305-5961 (office)

Telephone: 212-305-5967 (lab)

Fax: 212-305-6701

We thank following  funding sources:




- March of Dimes


- The Price Family Foundation

© 2023 by JIANWEN QUE Laboratory, Department of Medicine, Columbia University Medical Center

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